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Aviane

Generic name: ethinyl estradiol and levonorgestrelETH-in-ill-ess-tra-DYE-ol-and-LEE-vo-nor-JESS-trel ]
Drug class: Contraceptives

Medically reviewed by Philip Thornton, DipPharm. Last updated on Aug 23, 2023.

What is Aviane?

Aviane is a combination birth control pill containing female hormones that prevent ovulation (the release of an egg from an ovary). Aviane also causes changes in your cervical mucus and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus.

Aviane is used as contraception to prevent pregnancy.

Aviane does not protect against transmission of HIV (AIDS) and other sexually transmitted diseases (STDs) such as chlamydia, genital herpes, genital warts, gonorrhea, hepatitis B, and syphilis.

Warnings

Do not use Aviane if you are pregnant or if you have recently had a baby.

You should not use Aviane if you have: uncontrolled high blood pressure, heart disease, coronary artery disease, circulation problems (especially with diabetes), undiagnosed vaginal bleeding, liver disease or liver cancer, severe migraine headaches, if you also take certain hepatitis C medication, if you will have major surgery, if you smoke and are over 35, or if you have ever had a heart attack, a stroke, a blood clot, jaundice caused by pregnancy or birth control pills, or cancer of the breast, uterus/cervix, or vagina.

Taking birth control pills can increase your risk of blood clots, stroke, or heart attack.

Smoking can greatly increase your risk of blood clots, stroke, or heart attack. You should not take this medicine if you smoke and are over 35 years old.

Before taking this medicine

Taking this medicine can increase your risk of blood clots, stroke, or heart attack. You are even more at risk if you have high blood pressure, diabetes, high cholesterol, or if you are overweight. Your risk of stroke or blood clot is highest during your first year of taking Aviane. Your risk is also high when you restart this medicine after not taking it for 4 weeks or longer.

Smoking can greatly increase your risk of blood clots, stroke, or heart attack. Your risk increases the older you are and the more you smoke. You should not take Aviane if you smoke and are over 35 years old.

Do not use if you are pregnant. Stop using this medicine and tell your doctor right away if you become pregnant, or if you miss two menstrual periods in a row. If you have recently had a baby, wait at least 4 weeks before taking birth control pills.

You should not take Aviane if you have:

To make sure Aviane is safe for you, tell your doctor if you have ever had:

Aviane can slow breast milk production. You should not breastfeed while using this medicine.

How should I take Aviane?

Take Aviane exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Take your first pill on the first day of your period or on the first Sunday after your period begins. You may need to use back-up birth control, such as condoms or a spermicide, when you first start using this medicine. Follow your doctor's instructions.

Take one pill every day, no more than 24 hours apart. When the pills run out, start a new pack the following day. You may get pregnant if you do not take one pill daily. Get your prescription refilled before you run out of pills completely.

Some birth control packs contain seven "reminder" pills to keep you on your regular cycle. Your period will usually begin while you are using these reminder pills.

You should chew the chewable tablet (pill) and then swallow it with a glass of water, or if you prefer you should swallow the chewable tablet (pill) whole. Take it on an empty stomach.

Use a back-up birth control if you are sick with severe vomiting or diarrhea.

You may have breakthrough bleeding, especially during the first 3 months. Tell your doctor if this bleeding continues or is very heavy.

If you need major surgery or will be on long-term bed rest, you may need to stop using this medicine for a short time. Any doctor or surgeon who treats you should know that you are using Aviane.

While taking Aviane, you will need to visit your doctor regularly.

Store at room temperature away from moisture, heat, and light.

Dosing information

Usual Adult Dose for Contraception:

Oral tablets: 1 tablet orally once a day at the same time each day in the order directed on the blister pack.

What happens if I miss a dose?

Follow the patient instructions provided with your medicine. Missing a pill increases your risk of becoming pregnant.

If you miss one active pill, take two pills on the day that you remember. Then take one pill per day for the rest of the pack.

If you miss two active pills in a row in Week 1 or 2, take two pills per day for two days in a row. Then take one pill per day for the rest of the pack. Use back-up birth control for at least 7 days following the missed pills.

If you miss two active pills in a row in Week 3, throw out the rest of the pack and start a new pack the same day if you are a Day 1 starter. If you are a Sunday starter, keep taking a pill every day until Sunday. On Sunday, throw out the rest of the pack and start a new pack that day.

If you miss three active pills in a row in Week 1, 2, or 3, throw out the rest of the pack and start a new pack on the same day if you are a Day 1 starter. If you are a Sunday starter, keep taking a pill every day until Sunday. On Sunday, throw out the rest of the pack and start a new pack that day.

If you miss two or more active pills, you may not have a period during the month. If you miss a period for two months in a row, call your doctor because you might be pregnant.

If you miss a reminder pill, throw it away and keep taking one reminder pill per day until the pack is empty.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include nausea, vomiting, and drowsiness.

What should I avoid while taking Aviane?

Do not smoke while taking Aviane, especially if you are older than 35 years of age.

Birth control pills will not protect you from sexually transmitted diseases--including HIV and AIDS. Using a condom is the only way to protect yourself from these diseases.

Aviane side effects

Get emergency medical help if you have signs of an allergic reaction to Aviane: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using Aviane and call your doctor at once if you have:

Common Aviane side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Aviane?

Other drugs may interact with ethinyl estradiol and levonorgestrel, including prescription and over-the-counter medicines, vitamins, and herbal products. Some drugs can make Aviane less effective, which may result in pregnancy. Tell your doctor about all your current medicines and any medicine you start or stop using.

References

  1. Aviane Product Label
  2. Oral Contraceptives and Body Mass Index

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Aviane only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.